Laguna-S-2.1 runs on my 2020 PC (RTX 3080 10GB, Ryzen 9 3950X, 64 GB RAM). Realistically only usable overnight though. I must not breathe too hard or I run out of both VRAM and host RAM. There's just enough RAM left to run the compilation and unit tests of whatever coding project I hand to it. IQ4_X